transparent gif


Ej inloggad.

Göteborgs universitets publikationer

Intake of milk fat, reflected in adipose tissue fatty acids and risk of myocardial infarction: a case-control study

Författare och institution:
A. S. Biong (-); M. B. Veierod (-); J. Ringstad (-); Dag Thelle (Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa); J. I. Pedersen (-)
Publicerad i:
Eur J Clin Nutr, 60 ( 2 ) s. 236-44
0954-3007 (Print)
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
OBJECTIVE: To study the association between content of fatty acids from milk fat (14:0, 15:0 and 17:0) in adipose tissue and risk of a first myocardial infarction (MI). DESIGN AND SUBJECTS: A case-control study with 99 patients and 98 population controls both men and postmenopausal women, age 45-75 year. Adipose tissue fatty acids were determined by gas-liquid chromatography. RESULTS: The content of 14:0, 14:1, 15:0, 17:0 and 17:1 were all significantly higher in adipose tissue of controls than of the patients. Age and sex adjusted odds ratios (OR) for MI were significantly reduced with increasing quartiles of 14:0, 14:1, 15:0 and 17:1 in adipose tissue, but except for 15:0 (OR = 0.36, 95% CI 0.13-0.99), the trend was no longer significant after further adjustment for waist-to-hip ratio, smoking and family history for coronary heart disease. Correlations between 14:0 and 15:0 in adipose tissue, and waist-to-hip ratio were significantly negative (r = -0.22 for both, P < 0.01). CONCLUSION: Our study suggests that intake of dairy fat or some other component of dairy products, as reflected by C15:0 as marker in adipose tissue, may protect persons at increased risk from having a first MI, and that the causal effects may rely on other factors than serum cholesterol. SPONSORSHIP: Throne Holst's foundation for Nutrition Research, Research Council of Norway, The Norwegian Association of Margarine Producers, DeNoFa Fabriker A/S, TINE BA.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Hälsovetenskaper ->
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ->
Folkhälsomedicinska forskningsområden
Adipose Tissue/*chemistry, Age Factors, Aged, Animals, Case-Control Studies, Fatty Acids/*analysis/*metabolism, Female, Humans, Male, Middle Aged, Milk/*chemistry, Myocardial Infarction/*epidemiology/etiology/prevention & control, Odds Ratio, Risk Factors, Sex Factors, Waist-Hip Ratio
Postens nummer:
Posten skapad:
2007-10-12 13:56
Posten ändrad:
2011-01-20 10:00

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007