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Göteborgs universitets publikationer

The effects of endurance training in persons with a hereditary myosin myopathy

Författare och institution:
Katharina S Sunnerhagen (Institutionen för klinisk neurovetenskap); Niklas Darin (Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik); Homa Tajsharghi (Institutionen för laboratoriemedicin , Avdelningen för patologi); Anders Oldfors (Institutionen för laboratoriemedicin , Avdelningen för patologi)
Publicerad i:
Acta Neurol Scand, 110 ( 2 ) s. 80-6
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
OBJECTIVE: To evaluate muscle performance and its consequences in eight individuals with a hereditary myopathy and the effects of an 8-week endurance training program. MATERIAL AND METHODS: Handgrip, muscle strength and endurance and oxygen consumption by breath-by-breath analysis during a stepless bicycle ergonometer test were evaluated. Walking, balance test and activities of daily living (ADL) were assessed, and a questionnaire for activity level and perceived symptoms was used. The design was a before-after trial in comparison with data from a control population, bicycling at 70% of maximal workload, 30 min/day, 5 days/week for 8 weeks. RESULTS: The subjects were weaker than age-matched controls. After training, the peak watt increased by almost 20% (P < 0.05). Muscle strength (flexion/extension) and isometric endurance (40% of maximum at 60 degrees ) did not change significantly. The average self-selected walking speed increased significantly (P < 0.05) from 1.25 to 1.45 m/s. Compliance was excellent and no serious adverse events occurred. CONCLUSION: Endurance training seems to function for this myopathy.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin ->
Postens nummer:
Posten skapad:
2007-10-08 11:11
Posten ändrad:
2013-02-20 21:02

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