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Göteborgs universitets publikationer

Are predictors for myocardial infarction the same for women and men when evaluated prior to hospital admission?

Författare och institution:
L. Svensson (-); R. Nordlander (-); Christer Axelsson (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Johan Herlitz (Institutionen för medicin, avdelningen för molekylär och klinisk medicin)
Publicerad i:
Int J Cardiol, 109 ( 2 ) s. 241-7
0167-5273 (Print)
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
AIM: To describe predictors of myocardial infarction prior to hospital admission in women and men among patients with a suspected acute coronary syndrome without ST-elevation. DESIGN: Prospective observational study in Stockholm and Goteborg, Sweden. RESULTS: Of 433 patients who did fulfill the inclusion criteria 45% were women. Fewer women (17%) than men (26%) developed acute myocardial infarction (AMI) (p=0.054), particularly among patients with initial ST-depression, in whom AMI was developed in 22% of women and 54% of men (p = 0.001). Predictors for infarct development in women were: a history of AMI and advanced age. Among men they were: initial ST-depression or a Q-wave on ECG and elevation of biochemical markers (both recorded on admission of the ambulance crew). There was a significant interaction between gender and the influence of ST-depression on the risk for development of myocardial infarction (p < 0.05). CONCLUSION: Among patients transported with ambulance due to a suspected acute coronary syndrome and no ST-elevation fewer women than men seem to develop AMI particularly among patients with ST-depression. These results suggest that early prediction of myocardial infarction might differ between women and men with acute chest pain.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Aged, Aged, 80 and over, Analysis of Variance, Biological Markers/blood, Confounding Factors (Epidemiology), Coronary Arteriosclerosis/epidemiology/therapy, Data Collection, Electrocardiography, Female, Follow-Up Studies, Heart Conduction System/pathology, Humans, Male, Middle Aged, Myocardial Infarction/*diagnosis/*epidemiology/therapy, *Patient Admission, Predictive Value of Tests, Prospective Studies, Risk Factors, Sex Factors, Sweden/epidemiology
Postens nummer:
Posten skapad:
2007-09-27 16:16
Posten ändrad:
2010-01-26 12:48

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