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Göteborgs universitets publikationer

Treatment and short-term outcome in women and men with acute coronary syndromes

Författare och institution:
Elisabeth Perers (Hjärt-kärlinstitutionen); Kenneth Caidahl (Institutionen för fysiologi och farmakologi, Avdelningen för fysiologi); Johan Herlitz (Hjärt-kärlinstitutionen); B. W. Karlson (-); Thomas Karlsson (Hjärt-kärlinstitutionen); Marianne Hartford (Hjärt-kärlinstitutionen)
Publicerad i:
Int J Cardiol, 103 ( 2 ) s. 120-7
0167-5273 (Print)
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
OBJECTIVE: To study differences in treatment and early morbidity and mortality in relation to gender, type of acute coronary syndrome (ACS) and age in patients under 80 years of age. METHODS: We studied 1744 consecutive patients with ACS with assumed decreasing order of severity [ST-elevation myocardial infarction (MI), non-ST-elevation MI and unstable angina of high- and low-risk types] admitted to the coronary care unit at Sahlgrenska University Hospital. RESULTS: The use of thrombolysis and percutaneous coronary interventions (PCI) did not differ significantly between gender groups and women did not suffer from more severe complications than men. Treatment with beta-blockers, ACE inhibitors and aspirin was used on a similar scale among women and men. In-hospital complications and use of intravenous drugs were strongly associated with severity of disease in a similar way among women and men. The mortality rates at 30 days were 12.4% and 7.4% in MI with and without ST-segment elevation, but only 1.3% and 1.0% in unstable angina of high- and low-risk types. The use of primary PCI decreased with age, as did coronary angiography and PCI in the subacute phase, irrespective of gender. CONCLUSION: Among patients <80 years with ACS admitted to a coronary care unit, the suspicion that women are treated less aggressively than men could not be verified. Nor did women suffer from more complications or have a significantly higher 30-day mortality than men. Elderly patients were significantly less likely to undergo invasive procedures than those of a younger age, irrespective of gender.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Acute Disease, Adrenergic beta-Antagonists/therapeutic use, Age Factors, Aged, Angina, Unstable/radiography/therapy, *Angioplasty, Transluminal, Percutaneous Coronary, Angiotensin-Converting Enzyme Inhibitors/therapeutic use, Coronary Angiography, Coronary Disease/radiography/*therapy, Female, Fibrinolytic Agents/therapeutic use, Follow-Up Studies, Humans, Male, Middle Aged, Myocardial Infarction/radiography/therapy, Myocardial Reperfusion, Severity of Illness Index, Sex Factors, Survival Rate, Syndrome, Time Factors, Treatment Outcome
Postens nummer:
Posten skapad:
2007-09-27 16:07
Posten ändrad:
2011-01-20 09:59

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