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Göteborgs universitets publikationer

Laterality in five-year-olds conceived by intracytoplasmic sperm injection, standard in vitro fertilisation and natural conception: a European study

Författare och institution:
A G Sutcliffe (-); J Barnes (-); Ulla-Britt Wennerholm (Institutionen för kvinnors och barns hälsa, Avdelningen för obstetrik och gynekologi); A Loft (-); B C Tarlatzis (-); I Ponjaert-Kristoferson (-); M Bonduelle (-)
Publicerad i:
Bjog, 112 ( 10 ) s. 1397-401
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
OBJECTIVE: To assess laterality in a group of European children conceived with the help of assisted reproductive therapy, or naturally conceived. DESIGN: Prospective cohort study. SETTING: Five European countries. POPULATION: A total of 1525 five-year-old children divided into three groups according to conception status: naturally conceived; intracytoplasmic sperm injection (ICSI); in vitro fertilisation (IVF) group. METHODS: All children were assessed using the McCarthy Scale of Children's Abilities (Motor Scale) with additional items using a comb, a spoon and an indirect measure was made of the parental handedness scores, using a questionnaire. MAIN OUTCOME MEASURES: Child handedness for drawing and writing. RESULTS: Observed handedness did not differ significantly between natural conception, IVF and ICSI in girls or boys, except for ICSI-conceived girls, fewer of whom were left-handed than the naturally conceived controls, 7.0%versus 12.4% (P < 0.05), however, this was close to the population norm of 8%. The degree of parental handedness did not significantly vary in the three groups. CONCLUSIONS: Laterality, as assessed by handedness, may be marginally less common in girls conceived with assisted reproductive therapies than with children conceived naturally.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Adult, Analysis of Variance, Child, Preschool, Cohort Studies, Fathers/statistics & numerical data, Female, Fertilization/*physiology, *Fertilization in Vitro, Functional Laterality/*physiology, Humans, Male, Mothers/statistics & numerical data, Pregnancy, Prospective Studies, Risk Factors, *Sperm Injections, Intracytoplasmic
Postens nummer:
Posten skapad:
2007-09-24 14:26
Posten ändrad:
2011-01-20 10:00

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