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Göteborgs universitets publikationer

Geographical variation in incidence of prostate cancer in Sweden : Survey in the National Prostate Cancer Register

Författare och institution:
P Stattin (-); R Johansson (-); R Lodnert (-); O Andren (-); Anna Bill-Axelsson (-); Ola Bratt (-); Jan-Erik Damber (Institutionen för de kirurgiska disciplinerna, Avdelningen för urologi); M Hellström (-); Jonas Hugosson (Institutionen för de kirurgiska disciplinerna, Avdelningen för urologi); R Lundgren (-); M Törnblom (-); E Varenhorst (-); JE Johansson (-)
Publicerad i:
Scand J Urol Nephrol, 39 ( 5 ) s. 372-379
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
Objective. To investigate the geographical variation in prostate cancer incidence in Sweden, in particular the incidences of screening-detected tumours and curative treatment of prostate cancer. Material and methods. Data were retrieved from the National Prostate Cancer Register of Sweden for all cases of prostate cancer diagnosed in the year 2000-01. There were a total of 14 376 cases of prostate cancer and the mean total annual age-adjusted incidence was 197/100 000 men. There were 3318 cases in tumour category T1c, i.e. non-palpable tumours diagnosed during work-up for an elevated serum level of prostate-specific antigen, 1006 of which (30%) were asymptomatic and detected at a health check-up. Results. The difference between the counties with the lowest and highest age-adjusted incidences per 100 000 men of total prostate cancer was almost twofold (128 vs 217). The corresponding variation in incidence of category T1c tumours was more than fourfold (13 vs 60); the difference in incidence of T1c tumours detected in asymptomatic men was up to 10-fold (2 vs 20); and there was more than a fourfold variation in incidence of curative treatment between counties (13 vs 67). Measured incidences were mostly highest in urban regions and in counties with university hospitals. Conclusion. There are large geographical variations in prostate cancer incidence and in the frequency of curative treatment for prostate cancer in Sweden and there appear to be large geographical variations in the uptake of prostate cancer screening.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin ->
Urologi och njurmedicin ->
Urologi och andrologi
Incidence; prostate cancer; register; screening
Postens nummer:
Posten skapad:
2007-07-03 13:54
Posten ändrad:
2011-01-20 09:59

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