transparent gif

 

Ej inloggad.

Göteborgs universitets publikationer

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.

Författare och institution:
Frederik Nevens (-); Pietro Andreone (-); Giuseppe Mazzella (-); Simone I Strasser (-); Christopher Bowlus (-); Pietro Invernizzi (-); Joost P H Drenth (-); Paul J Pockros (-); Jaroslaw Regula (-); Ulrich Beuers (-); Michael Trauner (-); David E Jones (-); Annarosa Floreani (-); Simon Hohenester (-); Velimir Luketic (-); Mitchell Shiffman (-); Karel J van Erpecum (-); Victor Vargas (-); Catherine Vincent (-); Gideon M Hirschfield (-); Hemant Shah (-); Bettina Hansen (-); Keith D Lindor (-); Hanns-Ulrich Marschall (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Kris V Kowdley (-); Roya Hooshmand-Rad (-); Tonya Marmon (-); Shawn Sheeron (-); Richard Pencek (-); Leigh MacConell (-); Mark Pruzanski (-); David Shapiro (-)
Publicerad i:
The New England journal of medicine, 375 ( 7 ) s. 631-43
ISSN:
1533-4406
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Primary biliary cholangitis (formerly called primary biliary cirrhosis) can progress to cirrhosis and death despite ursodiol therapy. Alkaline phosphatase and bilirubin levels correlate with the risk of liver transplantation or death. Obeticholic acid, a farnesoid X receptor agonist, has shown potential benefit in patients with this disease.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Gastroenterologi
Nyckelord:
Adult, Aged, Alkaline Phosphatase, blood, Bile Acids and Salts, blood, Bone Density, drug effects, Chenodeoxycholic Acid, adverse effects, analogs & derivatives, therapeutic use, Double-Blind Method, Female, Fibroblast Growth Factors, blood, Humans, Liver Cirrhosis, etiology, Liver Cirrhosis, Biliary, blood, complications, drug therapy, Male, Middle Aged, Pruritus, chemically induced
Postens nummer:
240962
Posten skapad:
2016-08-30 15:45
Posten ändrad:
2016-09-09 15:12

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007