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Göteborgs universitets publikationer

Resistance exercise improves physical fatigue in women with fibromyalgia: a randomized controlled trial

Författare och institution:
Anna Ericsson (Institutionen för neurovetenskap och fysiologi & Centrum för personcentrerad vård vid Göteborgs universitet (GPCC)); Annie Palstam (Institutionen för neurovetenskap och fysiologi, sektionen för hälsa och rehabilitering); Anette Larsson (Centrum för personcentrerad vård vid Göteborgs universitet (GPCC) & Institutionen för neurovetenskap och fysiologi); Löfgren Monica (-); Indre Bileviciute-Ljungar (-); Jan Bjersing (Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning); Gerdle Björn (-); Kosek Eva (-); Kaisa Mannerkorpi (Institutionen för neurovetenskap och fysiologi, sektionen för hälsa och rehabilitering & Centrum för personcentrerad vård vid Göteborgs universitet (GPCC))
Publicerad i:
Arthritis Research & Therapy, 18 s. Article number: 176
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
Background: Fibromyalgia (FM) affects approximately 1–3 % of the general population. Fatigue limits the work ability and social life of patients with FM. A few studies of physical exercise have included measures of fatigue in FM, indicating that exercise can decrease fatigue levels. There is limited knowledge about the effects of resistance exercise on multiple dimensions of fatigue in FM. The present study is a sub-study of a multicenter randomized controlled trial in women with FM. The purpose of the present sub-study was to examine the effects of a personcentered progressive resistance exercise program on multiple dimensions of fatigue in women with FM, and to investigate predictors of the potential change in fatigue. Methods: A total of 130 women with FM (age 22–64 years) were included in this assessor-blinded randomized controlled multicenter trial examining the effects of person-centered progressive resistance exercise compared with an active control group. The intervention was performed twice a week for 15 weeks. Outcomes were five dimensions of fatigue measured with the Multidimensional Fatigue Inventory (MFI-20). Information about background was collected and the women also completed several health-related questionnaires. Multiple linear stepwise regression was used to analyze predictors of change in fatigue in the total population. Results: A higher improvement was found at the post-treatment examination for change in the resistance exercise group, as compared to change in the active control group in the MFI-20 subscale of physical fatigue (resistance group Δ –1.7, SD 4.3, controls Δ 0.0, SD 2.7, p = 0.013), with an effect size of 0.33. Sleep efficiency was the strongest predictor of change in the MFI-20 subscale general fatigue (beta = −0.54, p = 0.031, R2 = 0.05). Participating in resistance exercise (beta = 1.90, p = 0.010) and working fewer hours per week (beta = 0.84, p = 0.005) were independent significant predictors of change in physical fatigue (R2 = 0.14). Conclusions: Person-centered progressive resistance exercise improved physical fatigue in women with FM when compared to an active control group. Trial registration: NCT01226784.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Annan medicin och hälsovetenskap
Fibromyalgia, resistance exercise, fatigue, RCT
Postens nummer:
Posten skapad:
2016-08-08 11:16
Posten ändrad:
2016-08-18 11:11

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