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Göteborgs universitets publikationer

Diet-microbiota interactions as moderators of human metabolism

Författare och institution:
J. L. Sonnenburg (-); Fredrik Bäckhed (Wallenberglaboratoriet)
Publicerad i:
Nature, 535 ( 7610 ) s. 56-64
ISSN:
0028-0836
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
It is widely accepted that obesity and associated metabolic diseases, including type 2 diabetes, are intimately linked to diet. However, the gut microbiota has also become a focus for research at the intersection of diet and metabolic health. Mechanisms that link the gut microbiota with obesity are coming to light through a powerful combination of translation-focused animal models and studies in humans. A body of knowledge is accumulating that points to the gut microbiota as a mediator of dietary impact on the host metabolic status. Efforts are focusing on the establishment of causal relationships in people and the prospect of therapeutic interventions such as personalized nutrition.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin
Nyckelord:
human gut microbiome, carbohydrate-active enzymes, protein-coupled, receptor, regulatory t-cells, insulin-resistance, induced obesity, intestinal microbiota, energy-metabolism, bacterial metabolites, cardiovascular risk, Science & Technology - Other Topics
Postens nummer:
239623
Posten skapad:
2016-07-28 13:45
Posten ändrad:
2016-08-16 14:30

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