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Göteborgs universitets publikationer

Oxygen Monitoring Reduces the Risk for Retinopathy of Prematurity in a Mexican Population

Författare och institution:
L. C. Zepeda-Romero (-); Pia Lundgren (Institutionen för neurovetenskap och fysiologi); J. A. Gutierrez-Padilla (-); L. M. Gomez-Ruiz (-); M. Q. Corona (-); J. V. Orozco-Monroy (-); A. Barragan-Sanchez (-); J. C. Razo-Cervantes (-); Chatarina Löfqvist (Institutionen för neurovetenskap och fysiologi); Anna-Lena Hård (Institutionen för neurovetenskap och fysiologi); Ann Hellström (Institutionen för neurovetenskap och fysiologi)
Publicerad i:
Neonatology, 110 ( 2 ) s. 135-140
ISSN:
1661-7800
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Background: Retinopathy of prematurity (ROP), a potentially blinding disease, affects preterm infants. High levels of oxygen saturation are a well-known risk factor for ROP. Objectives: To assess the frequency of ROP type 1 needing treatment after improved oxygen monitoring (2011) in a Mexican preterm population selected for WINROP analyses and to retrospectively revalidate WINROP, an online surveillance system identifying infants at risk of developing ROP type 1. Methods: Preterm infants born with birth weight (BW) < 1,750 g and/or at gestational age (GA) <= 34 weeks, screened for ROP in 2012-2014 at the Hospital Civil de Guadalajara, Mexico were included (n = 151). Eighty-five infants with GA < 32 weeks qualified for WINROP analyses. GA, BW, maximal ROP stage, ROP treatment and weekly weights were recorded. The results in the present study were compared to those of a previous WINROP study in the same hospital (2005-2010; n = 352). Results: In the present WINROP cohort, 11.8% of the infants born at GA < 32 weeks received treatment compared to 51.0% of the infants in the previous WINROP cohort. One infant (3%) born at GA >= 32 weeks received treatment during the present study period compared to 35.6% during the previous period. WINROP displayed 80.0% sensitivity in infants born at GA < 32 weeks in the present study compared to 84.7% in the previous study. Conclusions: Uncontrolled oxygen supplementation is the major risk factor for severe ROP in infants born at GA >= 32 weeks. After improved oxygen monitoring, the frequency of ROP treatment was dramatically reduced at the Hospital Civil de Guadalajara, Mexico. (C) 2016 S. Karger AG, Basel.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin
Nyckelord:
Retinopathy of prematurity, Oxygen, Extremely preterm infants, WINROP algorithm, screening algorithm winrop, postnatal weight-gain, preterm infants, gestational-age, birth-weight, prediction, unit, Pediatrics
Postens nummer:
239495
Posten skapad:
2016-07-26 14:16
Posten ändrad:
2016-08-16 13:30

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