transparent gif

 

Ej inloggad.

Göteborgs universitets publikationer

Prognostic significance of pulsatile tinnitus in cervical artery dissection

Författare och institution:
L. Kellert (-); M. Kloss (-); A. Pezzini (-); S. Debette (-); D. Leys (-); V. Caso (-); V. N. Thijs (-); A. Bersano (-); E. Touze (-); Turgut Tatlisumak (Institutionen för neurovetenskap och fysiologi); C. Traenka (-); P. A. Lyrer (-); S. T. Engelter (-); T. M. Metso (-); C. Grond-Ginsbach (-)
Publicerad i:
European Journal of Neurology, 23 ( 7 ) s. 1183-1187
ISSN:
1351-5101
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Background and purposeOur aim was to investigate whether pulsatile tinnitus (PT) in cervical artery dissection (CeAD) has prognostic significance. MethodsAll CeAD patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) study with documentation of PT were analysed. The presence of PT was systematically assessed using a standardized questionnaire. Stroke severity at admission was defined according to the National Institutes of Health Stroke Scale (NIHSS). Excellent outcome after 3 months was defined as a modified Rankin Scale of 0-1. ResultsSixty-three of 778 patients (8.1%) reported PT. PT+ patients presented less often with ischaemic stroke (41.3% vs. 63.9%, P < 0.001), more often with dissection in the internal carotid artery (85.7% vs. 64.2%, P = 0.001), less often with vessel occlusion (19.0% vs. 34.1%, P = 0.017) and more often with excellent outcome at 3 months (92.1% vs. 75.4%, P = 0.002). Logistic regression analysis identified PT as an independent predictor of excellent outcome after 3 months [odds ratio (OR) 3.96, 95% confidence interval (CI) 1.22-12.87] adjusted to significant outcome predictors NIHSS on admission (OR 0.82, 95% CI 0.79-0.86), Horner syndrome (OR 1.95, 95% CI 1.16-3.29) and vessel occlusion (OR 0.62, 95% CI 0.40-0.94) and to non-significant predictors age, sex, pain and location of CeAD. ConclusionThe presence of PT in CeAD is associated with a benign clinical course and predicts a favourable outcome.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin
Nyckelord:
acute ischaemic stroke, cervical artery dissection, outcome, pulsatile tinnitus, risk-factors, diagnosis, gender, Neurosciences & Neurology
Postens nummer:
239456
Posten skapad:
2016-07-25 13:33
Posten ändrad:
2016-08-15 15:21

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007