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Crosswalk algorithms for the conversion of mean EQ-5D indices calculated with different value sets

Författare och institution:
Szilard Nemes (Institutionen för kliniska vetenskaper, sektionen för anestesi, biomaterial och ortopedi, Avdelningen för ortopedi); Göran Garellick (Institutionen för kliniska vetenskaper, sektionen för anestesi, biomaterial och ortopedi, Avdelningen för ortopedi); R. Salomonsson (-); Ola Rolfson (Institutionen för kliniska vetenskaper, sektionen för anestesi, biomaterial och ortopedi, Avdelningen för ortopedi)
Publicerad i:
Scandinavian Journal of Public Health, 44 ( 5 ) s. 455-461
ISSN:
1403-4948
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Aims: The EQ-5D questionnaire of EuroQol is an important tool, not only for researchers, but also for quality registers. Until 2013, Sweden did not have a country-specific value set to convert the EQ-5D health states into a single index. Commonly, the UK time trade-off (UK TTO) value set has been used. The study reported here aimed to establish an easy to use tool for the bidirectional crosswalk of the mean EQ-5D values based on two different value sets: the UK TTO and the Swedish TTO value sets. Methods: Using an artificial data set encompassing all possible EQ-5D outcomes, we calculated the EQ-5D index using both the UK TTO and Swedish TTO value sets. Thereafter we modelled the relationship between the two indices using least-squares regression and major axis regression. A series of simulations was run to assess the feasibility of the obtained crosswalk algorithms. Results: Major axis regression was superior to ordinary least-squares regression. Converting the mean EQ-5D values from the UK TTO scale to the Swedish TTO scale was more accurate than the inverse conversion. Values close to the floor and ceiling of the EQ-5D index were more challenging to crosswalk. Conclusions: We established algorithms based on major axis regression to crosswalk EQ-5D values based on the UK TTO and the Swedish TTO value sets. The presented algorithm may facilitate comparisons of EQ-5D values when only mean values are available. The existence of a crosswalk algorithm will ease the transition from the UK TTO to the Swedish TTO value set.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Ortopedi
Nyckelord:
EQ-5D index, Swedish time-trade-off, UK time-trade-off, crosswalk, major axis regression, quality-of-life, patient-reported outcomes, hip-arthroplasty register, health-status, rheumatoid-arthritis, general-population, sf-12, us, utilities, states, Public
Postens nummer:
238771
Posten skapad:
2016-07-01 11:00

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