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Göteborgs universitets publikationer

Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.

Författare och institution:
Yu-Ching Cheng (-); Tara M Stanne (Institutionen för biomedicin, avdelningen för patologi); Anne-Katrin Giese (-); Weang Kee Ho (-); Matthew Traylor (-); Philippe Amouyel (-); Elizabeth G Holliday (-); Rainer Malik (-); Huichun Xu (-); Steven J Kittner (-); John W Cole (-); Jeffrey R O'Connell (-); John Danesh (-); Asif Rasheed (-); Wei Zhao (-); Stefan Engelter (-); Caspar Grond-Ginsbach (-); Yoichiro Kamatani (-); Mark Lathrop (-); Didier Leys (-); Vincent Thijs (-); Tiina M Metso (-); Turgut Tatlisumak (-); Alessandro Pezzini (-); Eugenio A Parati (-); Bo Norrving (-); Steve Bevan (-); Peter M Rothwell (-); Cathie Sudlow (-); Agnieszka Slowik (-); Arne Lindgren (-); Matthew R Walters (-); Jim Jannes (-); Jess Shen (-); David Crosslin (-); Kimberly Doheny (-); Cathy C Laurie (-); Sandip M Kanse (-); Joshua C Bis (-); Myriam Fornage (-); Thomas H Mosley (-); Jemma C Hopewell (-); Konstantin Strauch (-); Martina Müller-Nurasyid (-); Christian Gieger (-); Melanie Waldenberger (-); Annette Peters (-); Christine Meisinger (-); M Arfan Ikram (-); W T Longstreth (-); James F Meschia (-); Sudha Seshadri (-); Pankaj Sharma (-); Bradford Worrall (-); Christina Jern (Institutionen för biomedicin, avdelningen för patologi); Christopher Levi (-); Martin Dichgans (-); Giorgio B Boncoraglio (-); Hugh S Markus (-); Stephanie Debette (-); Arndt Rolfs (-); Danish Saleheen (-); Braxton D Mitchell (-)
Publicerad i:
Stroke; a journal of cerebral circulation, 47 ( 2 ) s. 307-16
ISSN:
1524-4628
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Although a genetic contribution to ischemic stroke is well recognized, only a handful of stroke loci have been identified by large-scale genetic association studies to date. Hypothesizing that genetic effects might be stronger for early- versus late-onset stroke, we conducted a 2-stage meta-analysis of genome-wide association studies, focusing on stroke cases with an age of onset <60 years.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Medicinska grundvetenskaper ->
Medicinsk genetik
Nyckelord:
Adult, African Continental Ancestry Group, genetics, Age of Onset, Aged, Asian Continental Ancestry Group, genetics, Brain Ischemia, complications, genetics, Chromosomes, Human, Pair 10, Computer Simulation, DNA, Intergenic, genetics, European Continental Ancestry Group, genetics, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Middle Aged, Odds Ratio, Polymorphism, Single Nucleotide, Serine Endopeptidases, genetics, metabolism, Stroke, etiology, genetics
Postens nummer:
238483
Posten skapad:
2016-06-28 13:07

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