transparent gif

 

Ej inloggad.

Göteborgs universitets publikationer

Cardiovascular events after ischemic stroke in young adults: A prospective follow-up study

Författare och institution:
K. Aarnio (-); B. Siegerink (-); J. Pirinen (-); J. Sinisalo (-); M. Lehto (-); E. Haapaniemi (-); A. H. Nave (-); M. Kaste (-); Turgut Tatlisumak (Institutionen för neurovetenskap och fysiologi); J. Putaala (-)
Publicerad i:
Neurology, 86 ( 20 ) s. 1872-1879
ISSN:
0028-3878
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Objectives:To study the long-term risk of recurrent cardiac, arterial, and venous events in young stroke patients, and whether these risks differed between etiologic subgroups.Methods:The study population comprised 970 patients aged 15-49 years from the Helsinki Young Stroke Registry (HYSR) who had an ischemic stroke in 1994-2007. We obtained follow-up data until 2012 from the Finnish Care Register and Statistics Finland. Cumulative 15-year risks were analyzed with life tables, whereas relative risks and corresponding confidence intervals (CI) were based on hazard ratios (HR) from Cox regression analyses.Results:There were 283 (29.2%) patients with a cardiovascular event during the median follow-up of 10.1 years (range 0.1-18.0). Cumulative 15-year risk for venous events was 3.9%. Cumulative 15-year incidence rate for composite vascular events was 34.0 (95% CI 30.1-38.2) per 1,000 person-years. When adjusted for age and sex, patients with an index stroke caused by high-risk sources of cardioembolism had the highest HR for any subsequent cardiovascular events (3.7; 95% CI 2.6-5.4), whereas the large-artery atherosclerosis group had the highest HR (2.7; 95% CI 1.6-4.6) for recurrent stroke compared with patients with stroke of undetermined etiology.Conclusions:The risk for future cardiovascular events after ischemic stroke in young adults remains high for years after the index stroke, in particular when the index stroke is caused by high-risk sources of cardioembolism or large-artery atherosclerosis.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Medicinska grundvetenskaper ->
Neurovetenskaper
Nyckelord:
HOSPITAL DISCHARGE REGISTER, RECURRENT VASCULAR EVENTS, LONG-TERM, PROGNOSIS, ATHEROSCLEROTIC DISEASE, VENOUS THROMBOEMBOLISM, RISK, POPULATION, DEATH, AGE, CLASSIFICATION
Postens nummer:
238445
Posten skapad:
2016-06-28 10:31

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007