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Göteborgs universitets publikationer

EXPLANATORY FACTORS AND PREDICTORS OF FATIGUE IN PERSONS WITH RHEUMATOID ARTHRITIS: A LONGITUDINAL STUDY

Författare och institution:
Caroline Feldthusen (Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning); Anna Grimby-Ekman (Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa); Helena Forsblad d'Elia (Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning); Lennart Jacobsson (Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning); Kaisa Mannerkorpi (Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning)
Publicerad i:
Journal of Rehabilitation Medicine, 48 ( 5 ) s. 469-476
ISSN:
1650-1977
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Objective: To investigate the impact of disease-related aspects on long-term variations in fatigue in persons with rheumatoid arthritis. Methods: Sixty-five persons with rheumatoid arthritis, age range 20-65 years, were invited to a clinical examination at 4 time-points during the 4 seasons. Outcome measures were: general fatigue rated on visual analogue scale (0-100) and aspects of fatigue assessed by the Bristol Rheumatoid Arthritis Fatigue Multidimensional Questionnaire. Diseaserelated variables were: disease activity (erythrocyte sedimentation rate), pain threshold (pressure algometer), physical capacity (six-minute walk test), pain (visual analogue scale (0-100)), depressive mood (Hospital Anxiety and Depression scale, depression subscale), personal factors (age, sex, body mass index) and season. Multivariable regression analysis, linear mixed effects models were applied. Results: The strongest explanatory factors for all fatigue outcomes, when recorded at the same time-point as fatigue, were pain threshold and depressive mood. Self-reported pain was an explanatory factor for physical aspects of fatigue and body mass index contributed to explaining the consequences of fatigue on everyday living. For predicting later fatigue pain threshold and depressive mood were the strongest predictors. Conclusion: Pain threshold and depressive mood were the most important factors for fatigue in persons with rheumatoid arthritis.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Reumatologi och inflammation
Nyckelord:
fatigue, rheumatoid arthritis, longitudinal study, outcome assessment, physical-activity, disease-activity, pain, fibromyalgia, sleep, inflammation, association, reliability, sensitivity, perspective, Rehabilitation, Sport Sciences
Postens nummer:
237415
Posten skapad:
2016-06-07 15:25

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