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Göteborgs universitets publikationer

Centrally Mediated Disorders of Gastrointestinal Pain.

Författare och institution:
Laurie Keefer (-); Douglas A Drossman (-); Elspeth Guthrie (-); Magnus Simrén (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition); Kirsten Tillisch (-); Kevin Olden (-); Peter J Whorwell (-)
Publicerad i:
Gastroenterology, 150 ( 6 ) s. 1408–1419
ISSN:
1528-0012
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Centrally Mediated Abdominal Pain Syndrome (CAPS), formerly known as Functional Abdominal Pain Syndrome, can be distinguished from other functional GI disorders by its strong central component and relative independence from motility disturbances. CAPS is a result of central sensitization with disinhibition of pain signals rather than increased peripheral afferent excitability. A newly described condition, Narcotic Bowel Syndrome (NBS)/Opioid-Induced GI Hyperalgesia, is characterized by the paradoxical development of or increases in abdominal pain associated with continuous or increasing dosages of opioids. Patients only have relief when opioids are withdrawn. We define both conditions in the context of epidemiology, pathophysiology, clinical evaluation and treatment, emphasizing the importance of a physician-patient relationship in all aspects of care.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Gastroenterologi
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Invärtesmedicin
Postens nummer:
236001
Posten skapad:
2016-05-05 18:33
Posten ändrad:
2016-06-02 08:45

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