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Göteborgs universitets publikationer

Risk of intracranial hemorrhage in users of oral antithrombotic drugs: Study protocol for a nationwide study

Författare och institution:
Sasha Gulati (-); Ole Solheim (-); Sven M. Carlsen (-); Lise R. Øie (-); Heidi Jensberg (-); Agnete M. Gulati (-); Charalampis Giannadakis (-); Asgeir Store Jakola (Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering); Øyvind Salvesen (-)
Publicerad i:
F1000 Research, 4 s. 1519
E-ISSN:
2046-1402
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2015
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Background A wide range of antithrombotic medications can be used in the prevention and treatment of thrombosis. Among hemorrhagic complications of antithrombotic drugs, intracranial hemorrhage may have particularly devastating consequences with high morbidity, disability and mortality rates. The incidence and risks of intracranial hemorrhage in patients on antithrombotic treatments from regular clinical practice outside clinical trials remain largely unknown. It is not known if results from clinical trials can be extrapolated to everyday clinical practice. We will conduct a nationwide study to investigate the risks and incidence rates of intracranial hemorrhage in users oral antithrombotic drugs in Norway from 2008 through 2014. Methods and design The aim of this nationwide study is to investigate the incidence rates of intracranial hemorrhage requiring hospitalization in users of oral antithrombotic drugs. The study will be conducted within the approximately 4.7 million inhabitants of Norway from January 1st, 2008, to December 31st, 2014. Treatment and outcome data are obtained from the Norwegian patient registry and the Norwegian prescription database.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Hematologi
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Neurologi
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Kirurgi ->
Neurokirurgi
Postens nummer:
234379
Posten skapad:
2016-04-07 17:39
Posten ändrad:
2016-06-21 14:48

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