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Göteborgs universitets publikationer

Detection of cardiovascular risk from a photoplethysmographic signal using a matching pursuit algorithm.

Författare och institution:
Dirk Sommermeyer (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition); Ding Zou (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition); Joachim H Ficker (-); Winfried Randerath (-); Christoph Fischer (-); Thomas Penzel (-); Bernd Sanner (-); Jan A Hedner (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition); Ludger Grote (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition)
Publicerad i:
Medical & biological engineering & computing, 54 ( 7 ) s. 1111-1121
ISSN:
1741-0444
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2016
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Cardiovascular disease is the main cause of death in Europe, and early detection of increased cardiovascular risk (CR) is of clinical importance. Pulse wave analysis based on pulse oximetry has proven useful for the recognition of increased CR. The current study provides a detailed description of the pulse wave analysis technology and its clinical application. A novel matching pursuit-based feature extraction algorithm was applied for signal decomposition of the overnight photoplethysmographic pulse wave signals obtained by a single-pulse oximeter sensor. The algorithm computes nine parameters (pulse index, SpO2 index, pulse wave amplitude index, respiratory-related pulse oscillations, pulse propagation time, periodic and symmetric desaturations, time under 90 % SpO2, difference between pulse and SpO2 index, and arrhythmia). The technology was applied in 631 patients referred for a sleep study with suspected sleep apnea. The technical failure rate was 1.4 %. Anthropometric data like age and BMI correlated significantly with measures of vascular stiffness and pulse rate variability (PPT and age r = -0.54, p < 0.001, PR and age r = -0.36, p < 0.01). The composite biosignal risk score showed a dose-response relationship with the number of CR factors (p < 0.001) and was further elevated in patients with sleep apnea (AHI ≥ 15n/h; p < 0.001). The developed algorithm extracts meaningful parameters indicative of cardiorespiratory and autonomic nervous system function and dysfunction in patients suspected of SDB.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin
Nyckelord:
Matching pursuit, Neuro-fuzzy system, Photoplethysmography. Sleep, Cardiovascular risk
Postens nummer:
234326
Posten skapad:
2016-04-07 11:54
Posten ändrad:
2016-07-28 14:43

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