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Göteborgs universitets publikationer

Cortical thickness, volume and surface area in patients with bipolar disorder types I and II.

Författare och institution:
Christoph Abé (-); Carl-Johan Ekman (-); Carl Sellgren (-); Predrag Petrovic (-); Martin Ingvar (-); Mikael Landén (Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi)
Publicerad i:
Journal of psychiatry & neuroscience : JPN, 41 ( 4 ) s. 240-50
ISSN:
1488-2434
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2015
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Bipolar disorder (BD) is a common chronic psychiatric disorder mainly characterized by episodes of mania, hypomania and depression. The disorder is associated with cognitive impairments and structural brain abnormalities, such as lower cortical volumes in primarily frontal brain regions than healthy controls. Although bipolar disorder types I (BDI) and II (BDII) exhibit different symptoms and severity, previous studies have focused on BDI. Furthermore, the most frequently investigated measure in this population is cortical volume. The aim of our study was to investigate abnormalities in patients with BDI and BDII by simultaneously analyzing cortical volume, thickness and surface area, which yields more information about disease- and symptom-related neurobiology.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Psykiatri
Postens nummer:
231965
Posten skapad:
2016-02-12 14:24
Posten ändrad:
2016-08-05 13:24

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