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Göteborgs universitets publikationer

Lung count rate estimations using a portable scintillation detector prior to V/PSPECT

Författare och institution:
Malin Larsson (Institutionen för kliniska vetenskaper)
Publicerad i:
Swe-Rays, 26-28 aug 2015, Gothenburg, Sweden.,
Publikationstyp:
Konferensbidrag, poster
Publiceringsår:
2015
Språk:
engelska
Sammanfattning (abstract):
Purpose: The aim of this study was to find a method using a portable scintillation detector to predict the tomographic image statistics after inhaling technegas prior to V/PSPECT, and to validate the method for clinical use. Background: V/PSPECT is a tomographic imaging (SPECT) method using 99mTc labeled carbon particles (technegas) and 99mTc-MAA, for examination of the lung ventilation and perfusion, respectively using a gamma camera. Technegas is inhaled and a sufficient count rate is important in the ventilation images. A too low count rate gives inadequate image quality and a too high count rate can lead to difficulties when constructing quotient images between ventilation and perfusion images. To verify an acceptable count rate the local clinical routine is to use the camera detector. This method increases e.g. the risk of contaminating the camera head because of its air cooling system. It would be advantageous preparing the patient in another room using a portable detector; saving camera time, lower the risk of contaminate the camera and to see the count rate in real time. Method: A portable scintillation detector (SSL Radhound with SS404 Al probe Southern Scientific UK, via Gamma Data AB) was used and its characteristics like rotational symmetry, laterally size of detection field, distance dependence and the best placement of the detector was investigated. The contribution from the technegas in patient administration set (PAS) is relativelyhigh, and must be considered since only the count rate from the administrated technegas in the patient is of interest. Therefore an additional lead shield is placed on the detector. The positioning of the detector and the optimal height from the patient to the detector was investigated. The measurements were made with and without a PAS as well as with and without additional lead shielding to obtain a restricted field-of-view (FOV). To verify this method the number of counts in the diagnostic ventilation images was correlated to the portable detector count rate. Result: From measurements, the detector crystal was symmetric in response. The lateral size of the shielded FOV was a circle with a radius of 20 cm. Results: From these investigations the method of choice was to use an additional lead shield, and place the detector 20 cm above the xiphoid process whit the patient lying on the examination bed in supine position. The correlation between the diagnostic ventilation images and the portable detector count rate implies that a count rate of approximately 14 kcps is favorable to achieve adequate statistic in the tomographic images, when the patient administration set was removed. To obtain the recommended tomographic image statistics within a 95 % confidence interval, the total number of counts was calculated to be 800-2500 kCts, and then the count rate from the portable detector should be 12-15 kcps. Conclusion: Based on all tests performed in this project the most promising clinical method for this portable detector was determined. The portable detector should be placed on a fixed height 20 cm over the patient ́s xiphoid process. The count rate directly after the inhalation should be approximately 15 kcps. When the patient administration set is removed and the count rate is controlled again a sufficient value of the count rate is then 13-15 kcps. If the count rate is to low additional inhalation is needed.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin
Nyckelord:
Nuclear medicine V/PSPECT
Ytterligare information:
http://www.swerays.se/
Postens nummer:
229935
Posten skapad:
2016-01-06 18:20
Posten ändrad:
2016-05-31 09:03

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