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Göteborgs universitets publikationer

Associations Between Oral Health and Risk of Dementia in a 37-Year Follow-Up Study: The Prospective Population Study of Women in Gothenburg

Författare och institution:
R. Stewart (-); Ulrika Stenman (Institutionen för odontologi); Magnus Hakeberg (Institutionen för odontologi); Catharina Hägglin (Institutionen för odontologi); Deborah Gustafson (Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi); Ingmar Skoog (Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi)
Publicerad i:
Journal of the American Geriatrics Society, 63 ( 1 ) s. 100-105
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
ObjectivesTo investigate the association between incident dementia and previous number of teeth measured over a long interval. ParticipantsWomen with (n=158) and without (n=539) dementia in 2000 to 2005. MeasurementsTooth counts in 1968-69, 1980-81, and 1992-93. Covariates included age, education, stroke, myocardial infarction, diabetes mellitus, smoking status, blood pressure, body mass index, and cholesterol level. ResultsAfter adjustment for age, odds ratios (ORs) for dementia in 2000-05, comparing first with fourth tooth count quartiles, were 1.81 (95% confidence interval (CI)=1.03-3.19) for tooth counts measured in 1968, 2.25 (95% CI=1.18-4.32) for those in 1980, and 1.99 (0.92-4.30) for those in 1992. After further adjustment for education, ORs were 1.40 (95% CI=1.03-3.19) for 1968, 1.96 (95% CI=0.98-3.95) for 1980, and 1.59 (95% CI=0.71-3.53) for 1992, and after additional adjustment for vascular risk factors, ORs were 1.38 (95% CI=0.74-2.58) for 1968, 2.09 (95% CI=1.01-4.32) for 1980, and 1.61 (95% CI=0.70-3.68) for 1992. ConclusionIn most of the analyses, lower tooth count was not associated with dementia, although a significant association was found for one of the three examinations. Further research may benefit from more-direct measures of dental and periodontal disease.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin ->
dementia, tooth loss, oral health, periodontal disease, cohort study, ALZHEIMERS-DISEASE, COGNITIVE IMPAIRMENT, GENERAL DESIGN, DENTAL-HEALTH, EDENTULISM, NUTRITION, MORTALITY, DECLINE, PURPOSE, PEOPLE, Geriatrics & Gerontology, Gerontology
Postens nummer:
Posten skapad:
2015-03-11 10:22

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