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Göteborgs universitets publikationer

Gender differences in antihypertensive drug treatment: results from the Swedish Primary Care Cardiovascular Database (SPCCD).

Författare och institution:
Charlotta Ljungman (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Thomas Kahan (-); Linus Schiöler (Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa); Per Hjerpe (-); Jan Hasselström (-); Björn Wettermark (-); Kristina Bengtsson Boström (-); Karin Manhem (Institutionen för medicin, avdelningen för molekylär och klinisk medicin)
Publicerad i:
Journal of the American Society of Hypertension : JASH, 8 ( 12 ) s. 882-90
ISSN:
1878-7436
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2014
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
There are gender differences in antihypertensive treatment. This study aimed to investigate if gender differences in treatment could be explained by comorbidities. In addition, we aimed to study whether blood pressure control is different in women and men, and whether women interrupt treatment more often with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) compared with men.This cohort study within the Swedish Primary Care Cardiovascular Database included 40,825 patients with hypertension attending primary health care from 2007 to 2008. Cardiovascular comorbidities, with the exception of heart failure, were more common in men. Women were more often treated with diuretics, and men with ACEI, as were hypertensive patients with diabetes. Comorbidities could not entirely explain gender differences in antihypertensive treatment in a regression model. Women had higher systolic and lower diastolic blood pressure; this was also true in subgroups with cardiovascular comorbidity. Men more often than women were prescribed ACEIs/ARBs and interrupted treatment. Women and men are treated with different antihypertensive drugs, and this is not fully explained by differences in comorbidities. Women have higher systolic blood pressures, irrespective of comorbidity. Men have interrupted treatment more often with ACEIs/ARBs. These gender differences could affect outcome and warrant further investigation.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Invärtesmedicin
Postens nummer:
208679
Posten skapad:
2014-12-19 12:09
Posten ändrad:
2016-06-10 13:39

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