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Göteborgs universitets publikationer

Mortality and morbidity 1 year after early thrombolysis in suspected AMI: results from the TEAHAT Study.

Författare och institution:
Johan Herlitz (Hjärt-kärlinstitutionen); Mikael Dellborg (Hjärt-kärlinstitutionen); Marianne Hartford (Hjärt-kärlinstitutionen); Thomas Karlsson (Hjärt-kärlinstitutionen); Martin Risenfors (Hjärt-kärlinstitutionen); Björn W. Karlson (Hjärt-kärlinstitutionen); Russel Luepker (-); Stig Holmberg (Hjärt-kärlinstitutionen); Karl Swedberg (Hjärt-kärlinstitutionen); Åke Hjalmarson (Hjärt-kärlinstitutionen)
Publicerad i:
Journal of internal medicine. Supplement, 734 s. 43-51
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
We randomized 352 patients with suspected acute myocardial infarction (AMI) to treatment with rt-PA (n = 177) or placebo (n = 175). Patients were eligible if evaluated within 2 h and 45 min from onset of chest pain, and if aged less than 75 years. There were no ECG criteria for inclusion. A mobile coronary-care unit with a cardiologist present was used to initiate treatment at home in 29% of cases. During 1 year of follow-up the mortality in patients treated with rt-PA was 10.2%, as compared with 14.3% in patients the initial ECG, the mortality during the first year was 8% in the rt-PA group vs. 18% in the placebo group (P less than 0.05). Among patients without ST-elevation the mortality was 9% for the rt-PA group vs. 12% for the placebo group (NS). Requirement for rehospitalization, symptoms of angina pectoris and congestive heart failure, time of return to work and requirement for various medications did not differ significantly between the two groups, regardless of the initial ECG pattern.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin
Aged, Ambulatory Care, Angina Pectoris, mortality, Angioplasty, Balloon, Coronary, Coronary Artery Bypass, Electrocardiography, Exercise Test, Follow-Up Studies, Humans, Length of Stay, Myocardial Infarction, drug therapy, mortality, physiopathology, therapy, Survival Rate, Thrombolytic Therapy, Tissue Plasminogen Activator, therapeutic use
Postens nummer:
Posten skapad:
2014-06-30 11:14
Posten ändrad:
2016-08-24 13:16

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