transparent gif

 

Ej inloggad.

Göteborgs universitets publikationer

Seven-year follow-up of percutaneous closure of patent foramen ovale

Författare och institution:
Naqibullah Mirzada (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Per Ladenvall (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Per-Olof Hansson (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Magnus C Johansson (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Eva Furenäs (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Peter J Eriksson (Institutionen för medicin, avdelningen för molekylär och klinisk medicin); Mikael Dellborg (Institutionen för medicin, avdelningen för molekylär och klinisk medicin)
Publicerad i:
IJC Heart and Vessels, 1 s. 32-36
ISSN:
2214-7632
Publikationstyp:
Artikel, refereegranskad vetenskaplig
Publiceringsår:
2013
Språk:
engelska
Fulltextlänk:
Sammanfattning (abstract):
Background: Observational studies favor percutaneous closure of patent foramen ovale (PFO) over medical treatment to reduce recurrent stroke while randomized trials fail to demonstrate significant superiority of percutaneous PFO closure. Few long-term studies are available post PFO closure. This study reports long-term clinical outcomes after percutaneous PFO closure. Methods: Between 1997 and 2006, 86 consecutive eligible patients with cerebrovascular events, presumably related to PFO, underwent percutaneous PFO closure. All 86 patients were invited to a long-term follow-up, which was carried out during 2011 and 2012. Results: Percutaneous PFO closure was successfully performed in 85 of 86 patients. The follow-up rate was 100%. No cardiovascular or cerebrovascular deaths occurred. Two patients (both women) died from lung cancer during follow-up. Follow-up visits were conducted for 64 patients and the remaining 20 patients were followed up by phone. The mean follow-up time was 7.3. years (5 to 12.4. years). Mean age at PFO closure was 49. years. One patient had a minor stroke one month after PFO closure and a transient ischemic attack (TIA) two years afterwards. One other patient suffered from a TIA six years after closure. No long-term device-related complications were observed. Conclusions: Percutaneous PFO closure was associated with very low risk of recurrent stroke and is suitable in most patients. We observed no mortality and no long-term device-related complications related to PFO closure, indicating that percutaneous PFO closure is a safe and efficient treatment even in the long term. © 2013 Elsevier B.V.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
MEDICIN OCH HÄLSOVETENSKAP ->
Klinisk medicin ->
Kardiologi ->
Kardiovaskulär medicin
Nyckelord:
Cryptogenic stroke, Long-term follow-up, Patent foramen ovale (PFO), PFO closure, acetylsalicylic acid, clopidogrel, dipyridamole, warfarin, adult, article, atrioventricular block, computer assisted tomography, echocardiography, female, follow up, human, major clinical study, male, middle aged, nuclear magnetic resonance imaging, patent foramen ovale, percutaneous closure, priority journal, risk factor, safety, septal occluder, surgical technique, survival, transesophageal echocardiography, transient ischemic attack
Postens nummer:
195745
Posten skapad:
2014-03-26 18:04
Posten ändrad:
2016-06-10 13:21

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007