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Göteborgs universitets publikationer

Do non-communicable diseases such as hypertension and diabetes associate with primary open-angle glaucoma? Insights from a case-control study in Nepal.

Författare och institution:
Suraj Shakya-Vaidya (-); Umesh Raj Aryal (-); Madan Upadhyay (-); Alexandra Krettek (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition)
Publicerad i:
Global health action, 6 s. 22636
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
Background : Non-communicable diseases (NCDs) such as hypertension and diabetes are rapidly emerging public health problems worldwide, and they associate with primary open-angle glaucoma (POAG). POAG is the most common cause of irreversible blindness. The most effective ways to prevent glaucoma blindness involve identifying high-risk populations and conducting routine screening for early case detection. This study investigated whether POAG associates with hypertension and diabetes in a Nepalese population. Methods : To explore the history of systemic illness, our hospital-based case-control study used non-random consecutive sampling in the general eye clinics in three hospitals across Nepal to enroll patients newly diagnosed with POAG and controls without POAG. The study protocol included history taking, ocular examination, and interviews with 173 POAG cases and 510 controls. Data analysis comprised descriptive and inferential statistics. Descriptive statistics computed the percentage, mean, and standard deviation (SD); inferential statistics used McNemar's test to measure associations between diseases. Results : POAG affected males more frequently than females. The odds of members of the Gurung ethnic group having POAG were 2.05 times higher than for other ethnic groups. Hypertension and diabetes were strongly associated with POAG. The overall odds of POAG increased 2.72-fold among hypertensive and 3.50-fold among diabetic patients. Conclusion : POAG associates significantly with hypertension and diabetes in Nepal. Thus, periodic glaucoma screening for hypertension and diabetes patients in addition to opportunistic screening at eye clinics may aid in detecting more POAG cases at an early stage and hence in reducing avoidable blindness.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Hälsovetenskaper ->
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Postens nummer:
Posten skapad:
2013-11-28 13:28
Posten ändrad:
2013-12-13 15:41

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