transparent gif


Ej inloggad.

Göteborgs universitets publikationer

Orofacial functions and oral health associated with Treacher Collins syndrome.

Författare och institution:
Pamela Åsten (-); Nina Skogedal (-); Hilde Nordgarden (-); Stefan Axelsson (-); Harriet Akre (-); Lotta Sjögreen (Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering)
Publicerad i:
Acta odontologica Scandinavica, 71 ( 3-4 ) s. 616-25
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
Abstract Objective. The aim of this study was to describe orofacial features and functions and oral health associated with Treacher Collins syndrome (TCS) in relation to the variable phenotypic expression of the condition. Materials and methods. The Nordic Orofacial Test-Screening (NOT-S), MHC Questionnaire, MHC Observation chart and clinical examinations of nasal and pharyngeal conditions and chewing and swallowing function were used to assess 19 individuals aged 5-74 years (median 34 years). TCS severity scores were calculated by a clinical geneticist. Results. Orofacial features characterizing the study group were altered profile, increased mandibular angle, narrow hypopharynx and facial asymmetry. Basic orofacial functions such as breathing, eating, facial expression and speech were affected in all subjects demonstrating orofacial dysfunction in at least two NOT-S domains (median NOT-S total score 4/12, range 2-7). Significant correlation was found between the TCS severity scores reflecting phenotypic expression and the NOT-S total scores reflecting orofacial function. Self-reported experience of dry oral mucosa was common. Overall, dental health was good with few carious lesions diagnosed, but considerable need for orthodontic treatment was documented. Conclusions. Altered orofacial features and functions in TCS are common and often persist into late adolescence and adulthood. The functional level was correlated with the phenotypic variability of the condition. The standard of oral health was satisfactory. The findings indicated that individuals with TCS are likely to require lifelong health services related to their oral condition.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin
craniofacial disorder, dental care, NOT-S, orofacial feature, phenotype
Postens nummer:
Posten skapad:
2013-06-17 14:50
Posten ändrad:
2013-07-11 11:14

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007