transparent gif


Ej inloggad.

Göteborgs universitets publikationer

Determinants of Vitamin D Status in Fair-Skinned Women of Childbearing Age at Northern Latitudes

Författare och institution:
Linnea Hedlund (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition); Petra Brembeck (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition); Hanna Olausson (Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition)
Publicerad i:
PLoS ONE, 8 ( 4 ) s. Article Number: e60864
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
Background and Objective: Poor vitamin D status during pregnancy has been associated with unfavorable outcomes for mother and child. Thus, adequate vitamin D status in women of childbearing age may be important. The aim of this study is to investigate the determinants of 25-hydroxyvitamin D (25(OH)D) serum concentrations in women of childbearing age living in Sweden, at latitude 57-58 degrees north. Method: Eighty four non-pregnant, non-lactating, healthy, fair-skinned women aged between 25-40 years were included. All subjects provided blood samples, four day food records and answered questionnaires about sun exposure and lifestyle. Total serum 25(OH) D was analyzed using Roche Cobas (R) electrochemoluminiescent immunoassay. Results: Mean 25(OH) D was 65.8+/-19.9 nmol/l and 23% of the subjects had concentrations <50 nmol/l. Only 1% had concentrations <25 nmol/l. Determinants of 25(OH)D concentrations were recent sunbed use, recent travel to southern latitude, season, estrogen contraceptive use and use of supplementary vitamin D (R-2 = 0.27). Conclusion: Every fifth woman had 25(OH)D concentrations <50 nmol/l. About 30% of the variation in vitamin D status was explained by sun exposure, use of vitamin D supplements and use of estrogen contraceptives. Cutaneous vitamin D synthesis seems to be a major contributor to vitamin D status, even at northern latitudes. Thus, recommendations on safe UV-B exposure could be beneficial for vitamin D status.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin
Behavior, Cancers and neoplasms, Medicine, Micronutrient deficiencies, Nutrition, Obstetrics, Obstetrics and gynecology, Oncology, Osteopenia and osteoporosis, Pregnancy, Psychology, Public health, Public Health and Epidemiology, Research Article, Skin tumors, Vitamins, Women’s health
Postens nummer:
Posten skapad:
2013-06-07 09:21

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007