transparent gif


Ej inloggad.

Göteborgs universitets publikationer

Children and adolescents with follicular lymphoma have an excellent prognosis with either limited chemotherapy or with a "watch and wait" strategy after complete resection.

Författare och institution:
Andishe Attarbaschi (-); Auke Beishuizen (-); Georg Mann (-); Angelo Rosolen (-); Tetsuya Mori (-); Anne Uyttebroeck (-); Felix Niggli (-); Monika Csoka (-); Zdenka Krenova (-); Karin Mellgren (Institutionen för kliniska vetenskaper, sektionen för kvinnors och barns hälsa, Avdelningen för pediatrik); Edita Kabickova (-); Alan Ks Chiang (-); Alfred Reiter (-); Denise Williams (-); Birgit Burkhardt (-)
Publicerad i:
Annals of hematology, 92 ( 11 ) s. 1537-1541
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
Data on clinical features and outcome in pediatric follicular lymphoma (pFL) are scarce. The aim of this retrospective study including 13 EICNHL and/or i-BFM study group members was to assess clinical characteristics and course in a series of 63 pFL patients. pFL was found to be associated with male gender (3:1), older age (72 % ≥10 years old), low serum LDH levels (<500 U/l in 75 %), grade 3 histology (in 88 %), and limited disease (87 % stage I/II disease), mostly involving the peripheral lymph nodes. Forty-four out of sixty-three patients received any polychemotherapy and 1/63 rituximab only, while 17/63 underwent a "watch and wait" strategy. Of 36 stage I patients, 30 had complete resections. Only one patient relapsed; 2-year event-free survival and overall survival were 94 ± 5 and 100 %, respectively, after a median follow-up of 2.2 years. Conclusively, treatment outcome in pFL seems to be excellent with risk-adapted chemotherapy or after complete resection and an observational strategy only.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin ->
Follicular lymphoma, Complete resection, “Watch and wait”, Outcome
Postens nummer:
Posten skapad:
2013-05-22 10:47
Posten ändrad:
2013-11-07 11:38

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007