Risk för att prolaktinom växer under graviditet
Materials and methods: A retrospective study of 73 women with prolactinoma (97 pregnancies) who were examined at the neuro-ophthalmologic clinic at Sahlgrenska Universitetssjukhuset 2002-2010.
Results: One of 62 women with microprolactinoma (1.2 per cent of the pregnancies and 1.6 per cent of the women) and 1 of 11 women with macroprolactinoma (9.1 per cent of the pregnancies and 7.1 per cent of the women) developed visual field defects during pregnancy due to tumour growth. Both women experienced visual symptoms.
Conclusions: This study confirms that tumour growth causing visual field defects is rare during pregnancy, although more common with macro- than with microprolactinomas. Based on this and previous studies we conclude that women with microprolactinoma do not need visual field examinations during pregnancy due to a very low risk of non-symptomatic tumour growth, while for women with macroprolactinoma repeated visual field examinations during pregnancy should be considered.