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Göteborgs universitets publikationer

Surgical Reconstruction of Peri-Implant Bone Defects with Prehydrated and Collagenated Porcine Bone and Collagen Barriers: Case Presentations.

Författare och institution:
Christer Slotte (-); Ninita Lindfors (Institutionen för kliniska vetenskaper, sektionen för anestesi, biomaterial och ortopedi); Ulf Nannmark (Institutionen för biomedicin, avdelningen för medicinsk kemi och cellbiologi)
Publicerad i:
Clinical implant dentistry and related research, Early View
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
Background: Surgical reconstruction of peri-implant defects is challenging and unpredictable due to, for example, the extent of the bone defect or the osteogenic potential of adjunctive materials used. Purpose: To study the healing capacity of a new bone xenograft material in the treatment of peri-implant defects. Material and Methods: In three cases with advanced peri-implant defects, flap surgery was performed. After thorough debridement including cleaning of the exposed implant surface, prehydrated and collagenated porcine bone (PCPB) particles were placed into the defect. A bioresorbable collagen barrier was adapted and placed over the defect and the flaps were relocated. After 6 and 12 months of healing, clinical and radiographic examinations were done. In one case, the surgical procedure was repeated 6 months postoperatively. One year after the second surgery, a bone biopsy was harvested and analyzed with histology. Results: All defects healed uneventfully. At 6 months, probing depths were reduced by 3-4 mm with no bleeding on probing or pus formation. At 12 months, healthy peri-implant conditions were found. Intra-oral radiographs showed gain of the marginal bone level by 2-4 mm. In the case where reconstructive surgery was repeated, histology showed osteoconductive properties as bone formation with typical osteoblastic seams was observed directly on the surface of the grafted particles. Conclusion: The presented cases show that PCPB have favorable properties enhancing bone regeneration in peri-implant bone defects.
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin ->
Odontologi ->
bone substitute; peri-implantitis; xenogeneic bone; xenograft
Postens nummer:
Posten skapad:
2011-12-14 11:03
Posten ändrad:
2012-06-26 08:52

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