transparent gif


Ej inloggad.

Göteborgs universitets publikationer

Chromosome 22q11 deletion syndrome (CATCH 22): neuropsychiatric and neuropsychological aspects.

Författare och institution:
Lena Niklasson (Institutionen för kvinnors och barns hälsa, Avdelningen för barn- och ungdomspsykiatri); Peder Rasmussen (Institutionen för kvinnors och barns hälsa, Avdelningen för barn- och ungdomspsykiatri); Sólveig Oskarsdóttir (Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik); Christopher Gillberg (Institutionen för kvinnors och barns hälsa, Avdelningen för barn- och ungdomspsykiatri)
Publicerad i:
Developmental Medicine and Child Neurology, 44 ( 1 ) s. 44-50
Artikel, refereegranskad vetenskaplig
Sammanfattning (abstract):
Twenty children and young adults (age range 5 to 33 years, 12 females and eight males) with genetically confirmed 22q11 deletion syndrome (CATCH 22: Cardiac anomaly, Anomalous face, Thymus hypoplasia/aplasia, Cleft palate, and Hypocalcaemia), recruited from a large ongoing study, were given comprehensive assessments with a view to determining the pattern of neuropsychiatric and neuropsychological deficits thought to be part of the syndrome in many cases. IQ ranged between 46 and 100 with a mean score of 70. Half the group had an IQ <70. In 13 individuals, attention-deficit–hyperactivity disorder (ADHD), mainly inattentive or combined type in most cases, and/or autism spectrum problems were diagnosed. Many participants, even among those who had an IQ within the normal range and had neither ADHD nor autistic spectrum problems, showed a characteristic and pronounced behavioural profile with low mental energy, initiation difficulties, deficits in sustained attention, and social interaction (often augmented by limited facial expression and communication and speech problems).
Ämne (baseras på Högskoleverkets indelning av forskningsämnen):
Klinisk medicin ->
Abnormalities, Multiple, Genetics, Psychology, Adolescent, Adult, Attention, Attention Deficit Disorder with Hyperactivity, Etiology, Autistic Disorder, Etiology, Child, Child Behavior Disorders, Etiology, Child, Preschool, Chromosome Deletion, Chromosomes, Human, Pair 22, Genetics, Cleft Palate, Cognition Disorders, Etiology, Face, Abnormalities, Female, Heart Defects, Congenital, Humans, Hypocalcemia, Intelligence, Male, Social Behavior Disorders, Syndrome, Thymus Gland, Abnormalities, Pathology
Postens nummer:
Posten skapad:
2011-07-19 12:26

Visa i Endnote-format

Göteborgs universitet • Tel. 031-786 0000
© Göteborgs universitet 2007